Wheat Germ Agglutinin—From Toxicity to Biomedical Applications

نویسندگان

چکیده

Wheat germ agglutinin is a hevein class N-Acetylglucosamine–binding protein with specific toxicity and biomedical potential. It extractable from wheat germ—a low-value byproduct of the industry—using well–established extraction methods based on salt precipitation affinity chromatography. Due to its N-Acetylglucosamine affinity, exhibits antifungal properties as well cytotoxic properties. Its anticancer have been demonstrated for various cancer cells, mechanisms are described. has viable solution therapeutic applications, such chemotherapy, targeted drug delivery, antibiotic-resistant bacteria monitoring elimination. This performed mostly in conjunction nanoparticles, liposomes, other carrier via surface functionalization. Combined abundant sources, potential improve field considerably.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2021

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app11020884